To help avoid interactions, your doctor should manage all of your medications carefully. Do not take these drugs with bupropion. Doing so can cause dangerous effects in your body. Examples of these drugs include:. Taking bupropion with certain medications raises your risk for side effects from these drugs.
When bupropion is used with certain drugs, it may not work as well to treat your condition. This is because the amount of bupropion in your body may be decreased. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions.
Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Taking it again could be fatal cause death. When taking bupropion, your risk for seizures increases if you have too many drinks that contain alcohol.
If you drink alcohol, talk with your doctor about whether this drug is safe for you. For people with a seizure disorder: This drug raises the risk of seizures. You should not take this drug if you have a seizure disorder. For people with eating disorders such as bulimia or anorexia: This drug raises your risk for seizures. You should not take this drug if you have an eating disorder. For people with bipolar disorder: This drug may make your condition worse.
You should not take this drug if you have bipolar disorder. For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of this drug in your body and cause more side effects. Your doctor may reduce your dosage of this drug, or how often you are given this drug. For people with liver disease: Your doctor may reduce your dosage of this drug, or how often you are given this drug.
For people with angle-closure glaucoma: This drug can make your condition worse. For pregnant women: This drug is a category C pregnancy drug. That means two things:. This drug should only be used if the potential benefit justifies the potential risk. For women who are breastfeeding: This drug passes into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.
For seniors: The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time.
This raises your risk for side effects. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. It has not been confirmed that this drug is safe and effective for use in people younger than 18 years.
The kidneys of older adults may not work as well as they used to. This raises your risk of side effects. Treatment with this drug should start before you plan to quit smoking.
You should set a target quit date within the first 2 weeks of treatment with this drug. Treatment should be continued for 7—12 weeks. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you.
Bupropion oral tablet is used for long-term treatment of depression or SAD. Or you may not be able to quit smoking. For this drug to work well, a certain amount needs to be in your body at all times. If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include:.
Bupropion is available in several dosages. Certain brands of bupropion may contain a different dosage per tablet. For depression, a typical starting dosage of bupropion is mg to mg per day, taken either as mg tablets taken twice per day or a single mg extended-release bupropion tablet taken in the morning.
The maximum dosage of bupropion for depression is mg to mg per day. After three to four days, you may need to adjust your dosage of bupropion.
Follow the dosage instructions provided by your healthcare provider to make sure you take the right amount of bupropion. For smoking cessation, a typical starting dosage is one mg extended-release tablet per day for the first three days, followed by a dosage of mg per day, taken as two tablets taken at least eight hours apart, from day four.
Based on your symptoms, health history, response to the medication and several other factors, your healthcare provider may adjust your dosage of bupropion over time. Like all antidepressants, bupropion can cause certain side effects. Most of the side effects that can occur with bupropion are minor and temporary. However, there are also several potentially severe side effects that you should be aware of before using this medication.
Some of the common side effects of bupropion include:. Many of these side effects may be mild and often disappear over the course of several days or weeks. In general, bupropion is less likely to cause sexual dysfunction than other commonly prescribed antidepressants, such as SSRIs and tricyclic antidepressants. Like other antidepressants, bupropion may cause serious side effects. These side effects occur in a small percentage of bupropion users. Serious side effects of bupropion include:.
Mental health issues, such as panic attacks, changes in mood, impulsive behavior and worsened depression or anxiety. Bupropion may contribute to hypertension high blood pressure. If you have high blood pressure or a history of cardiovascular issues, make sure you inform your healthcare provider before using bupropion. Though rare, depending on dosage, anywhere from. Conditions that may increase your seizure risk include:. Use of other drugs that may affect your seizure susceptibility, such as other antidepressants, antipsychotics, systemic corticosteroids or theophylline.
Bupropion may also not be a suitable treatment for people with liver or kidney issues, diabetes or certain mental health conditions such as bipolar disorder. This warning is found on bupropion medications used for treating depression — bupropion smoking cessation aids do not carry the same warning.
Studies do not show that this risk occurs in people aged 24 and older. Bupropion can interact with other medications, including over-the-counter medications, herbal products and health supplements. These interactions may increase the amount of bupropion in your body or make the medication less effective. In some cases, the use of bupropion can cause dangerous interactions with other medications.
It was FDA approved in for the treatment of major depressive disorder. Wellbutrin SR is usually taken as mg twice daily for a total daily dose of mg. It was FDA approved in for major depressive disorder and seasonal affective disorder. Wellbutrin XL is absorbed in the body more slowly. Compared to immediate-release and sustained-release bupropion, the XL form releases the drug over a longer period of time.
For this reason, Wellbutrin XL is taken as a once-daily tablet. Sign up for Wellbutrin SR price alerts and find out when the price changes! Get price alerts. Both Wellbutrin SR and Wellbutrin XL are indicated to treat symptoms of major depression otherwise known as major depressive disorder.
However, Wellbutrin XL is also approved to prevent seasonal affective disorder. Seasonal affective disorder is a mood disorder that affects some people during seasonal changes. Wellbutrin XL can be started in the fall season to prevent mood changes in the winter.
Bupropion can be used in off-label ways to treat ADHD attention-deficit hyperactivity disorder , depressive episodes of bipolar disorder , and sexual dysfunction caused by other antidepressants like SSRIs selective serotonin reuptake inhibitors and tricyclic antidepressants. Other off-label indications include social phobia and PTSD post-traumatic stress disorder. Bupropion is sometimes used in combination with naltrexone to treat obesity and weight-related conditions.
Bupropion can help with smoking cessation. Bupropion for smoking cessation is manufactured under a different brand called Zyban. Zyban and Wellbutrin cannot be substituted for one another due to differences in dosing. Their uses and differences in dosing hold the most weight when choosing between the two. In a clinical study comparing bupropion SR and bupropion XL, those taking the once-daily bupropion XL experienced lower rates of depression and relapse.
Clinical trials found that there was more consistent use with the once-daily pill, most likely due to the ease of use. Those taking the twice-daily bupropion SR may have had more trouble taking both doses consistently. In a systematic review of bupropion , the XL formulation was found to be favored over placebo for preventing seasonal affective disorder. Controlled trials within the review showed a significant decrease in depressive symptoms in those affected with seasonal affective disorder.
Both forms of Wellbutrin are useful for treating some of the same conditions. Based on your medical history, you may be prescribed a different antidepressant. Sign up for Wellbutrin XL price alerts and find out when the price changes!
Wellbutrin SR is available as a generic oral tablet. It is usually covered by Medicare and most insurance plans. If you use a SingleCare discount card for generic bupropion, the cost can be reduced to a more affordable price.
Get the SingleCare prescription discount card. The generic version of Wellbutrin XL is typically covered by Medicare and other insurance plans. Check to see if your pharmacy accepts SingleCare cards for prescription discounts. Other side effects involve the CNS central nervous system and include dizziness, insomnia, and anxiety. Wellbutrin can also cause gastrointestinal side effects such as stomach upset and constipation.
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